Biuletyn COVID-19: Nowe kliniczne manifestacje

Większość hospitalizowanych z powodu Covid-19 uskarża się na co najmniej jeden problem zdrowotny
Esculap.com
Stan zdrowia pacjentów sprawdzano podczas wizyt kontrolnych między 16 czerwca a 3 września (średni czas monitorowania wynosił 186 dni).
Naukowcy wyliczyli, że 76 proc. chorych (spośród 1655 uwzględnionych w analizie) po upływie pół roku skarżyło się na jeden z problemów zdrowotnych, takich jak: zmęczenie i osłabienie mięśni – 63 proc., problemy ze snem – 26 proc., lęki i depresja – 23 proc.

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32656-8/fulltext#%20

Brain Imaging Points to Possible Reason for Persistent Smell, Taste Trouble in COVID Patients
Brain Imaging Points to Possible Reason for Persistent Smell, Taste Trouble in COVID Patients (medscape.com)
The researchers generated blood oxygen level-dependent (BOLD) activation maps fused to T1-weighted multiplanar images. The noteworthy finding, they say, was "absent activation in the region of the OFC, while the right uncus/piriform cortex demonstrated strong BOLD signal."

Fatigue, Brain Fog Most Common in 'Long COVID'
Fatigue, Brain Fog Most Common in 'Long COVID' (medscape.com)
About 65% of respondents experienced symptoms for at least 6 months. They most often reported fatigue, post-exercise malaise and brain fog, but they also highlighted neurological sensations, headaches, memory issues, muscle aches, insomnia, heart palpitations, shortness of breath, dizziness, balance issues and speech issues. Less common symptoms included facial paralysis, new allergies, seizures, impaired vision and hearing and a prolonged loss of taste and smell.

15 stycznia 2021

Zaobserwowane konsekwencje COVID-19 utrzymujące się po 6 miesiącach od zakażenia
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32656-8/fulltext#.X_tCGnqOiH8.twitter
Najczęstszymi objawami utrzymującymi się wśród badanych pacjentów po 6 miesiącach od zakażenia było zmęczenie, osłabienie mięśni, trudności ze snem, zaburzenia lękowe i depresja.

23 grudnia 2020

Long COVID guidelines need to reflect lived experience
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32705-7/fulltext?dgcid=hubspot_email_newsletter_tlcoronavirus20&utm_campaign=tlcoronavirus20&utm_medium=email&_hsmi=103959364&_hsenc=p2ANqtz-8j04fgDzwvQLetjTNL3dO2TBCwjw1mQyiAUxGQwUCUpWdQCE74IJ_B6tprqg8PutMj5WMED9LAzMtHEXwfcpmwd9uxQZpaEerRhkZtWTW6k-tQgWM&utm_content=103959364&utm_source=hs_email
Our symptoms of acute COVID-19 included dyspnoea, dry cough, fever, anosmia, and debilitating fatigue. Throughout 2020 we also experienced other symptoms and conditions, never experienced before our acute illnesses (panel).

16 grudnia 2020

SARS-CoV-2 uszkadza czerwone krwinki i może hamować powstawanie nowych
Wirus SARS-CoV-2 uszkadza czerwone krwinki i może hamować powstawanie nowych | Nauka w Polsce (pap.pl)
Wirus uszkadza czerwone krwinki i może hamować proces ich odnowy – wynika z rosyjsko-japońskich badań. W ten sposób infekcja przyczynia się do niedotlenienia tkanek i narządów.

27 listopada 2020

Epidemia negatywnie wpływa na jakość snu
https://bezsennosc.esculap.com/news/160692/epidemia-negatywnie-wpywa-na-jako-snu?utm_campaign=goniec2070&utm_source=esculap_wszyscy&utm_medium=goniec&utm_content=L31&link_id=243767
Z ankiety przeprowadzonej na ponad 4 tys. mieszkańców Finlandii wynika, że w grupie liczącej prawie osiemset osób wystąpiły koszmary, co autorzy ocenili jako przejaw wewnętrznego niepokoju.

Long COVID - kolejny efekt pandemii. https://thorax.bmj.com/content/early/2020/11/09/thoraxjnl-2020-215818?fbclid=IwAR09iDABGo3KxIcZR3b-ZboAx0lLjOT75Qg0GIl5zpYb_LO5pE-n6fwRBLg
Dane te są zgodne z badaniami opisującymi długoterminowe nieprawidłowości u osób, które przeszły zakażenie SARS , oraz wstępnymi danymi pochodzącymi z mniejszych kohort pacjentów z COVID-19.

17 listopada 2020

'Breakthrough Finding' Reveals Why Certain COVID Patients Die
https://www.medscape.com/viewarticle/940968?src=wnl_edit_tpal&uac=73796MK&impID=2676272&faf=1
In some cases, provocative new research shows, some people — men in particular — succumb because their immune systems are hit by friendly fire. Researchers hope the finding will help them develop targeted therapies for these patients.

10 listopada 2020

Living with Covid19
https://evidence.nihr.ac.uk/themedreview/living-with-covid19/
A dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid).

Denmark to cull up to 17 million mink amid coronavirus fears
htps://www.bbc.com/news/world-europe-54818615
The big public health concern is that any mutation to the coronavirus as it passes between mink and humans might be enough to stop human vaccines working, if and when they become available. Some scientists are now calling for a complete ban on mink production, saying it impedes our response and recovery from the pandemic.
https://www.youtube.com/channel/UCF9IOB2TExg3QIBupFtBDxg

Mutation update and UK flattening
https://www.youtube.com/watch?v=HjvyNfdbWy8

Mink and COVID-19
https://coronasmitte.dk/en/mink-farms

SARS-CoV-2 mink-associated variant strain – Denmark
https://www.who.int/csr/don/06-november-2020-mink-associated-sars-cov2-denmark/en/

29 października 2020

COVID-19 GI Symptoms Common, Tied to More Severe Disease, Worse Outcomes
https://www.medscape.com/viewarticle/939825?src=wnl_edit_tpal&uac=73796MK&impID=2646136&faf=1
"Patients with diarrhea likely harbor increased viral load, which can potentially lead to an increased systemic response to the virus and associated respiratory complications from it. Early recognition of patients is needed for prompt management of this at-risk population,"

"These results indicate that presenting with GI symptoms may place COVID-19 patients at a markedly higher risk of a worsened disease course from COVID-19 and need to be considered at the time of triage,"

Long COVID 'May Be Four Syndromes'
https://www.medscape.com/viewarticle/939168?src=mkm_ret_201029_mscpmrk_eumonthly_int&uac=73796MK&impID=2643364&faf=1
The condition commonly called 'long COVID' may not be one syndrome but possibly up to four different syndromes, according to a new review.

The finding comes from a dynamic themed review of available scientific evidence published by the National Institute for Health Research (NIHR).

The review found clear consistencies for a wide range of recurring symptoms among people who had been hospitalised because of COVID-19, as well as those who had COVID-19 in the community.

27 października 2020

Long-Haulers Are Redefining COVID-19
https://www.theatlantic.com/health/archive/2020/08/long-haulers-covid-19-recognition-support-groups-symptoms/615382/
Without understanding the lingering illness that some patients experience, we can’t understand the pandemic.

Attributes and predictors of Long-COVID: analysis of COVID cases and their symptoms collected by the Covid Symptoms Study App
https://www.medrxiv.org/content/10.1101/2020.10.19.20214494v1
Long-COVID was characterised by symptoms of fatigue, headache, dyspnoea and anosmia and was more likely with increasing age, BMI and female sex.

Long term COVID - dr John Campbell
https://www.youtube.com/watch?v=YN8y_VV6a7w
Zobaczmy też prezentacje na ten temat.

15 października 2020

Powstanie ośrodek leczenia pocovidowych zaburzeń psychicznych
https://psychiatria.esculap.com/news/160475/powstanie-orodek-leczenia-pocovidowych-zaburze-psychicznych?utm_campaign=goniec2051&utm_source=esculap_wszyscy&utm_medium=goniec&utm_content=L23&link_id=238994
Jedyny – zdaniem pomysłodawców – jak dotąd w Europie ośrodek dla „pacjentów, którzy mają problemy pocovidowe” ma zostać utworzony w budynku byłej szkoły w Smolnikach

Włoscy lekarze apelują, by nie szczepić się przeciwko grypie
https://forumszczepien.esculap.com/aktualnosc/id,160456?utm_campaign=goniec2051&utm_source=esculap_wszyscy&utm_medium=goniec&utm_content=L29&link_id=238997
Włoscy lekarze apelują, aby nie szczepić się przedwcześnie przeciwko grypie, ponieważ – jak tłumaczą – choroba nadejdzie później. Przypominają, że szczepionka działa trzy miesiące, a szczytu zachorowań należy spodziewać się pod koniec zimy.

13 października 2020

Long COVID
https://www.medexpress.pl/long-covid/79179
Pojawił się oto stan określany jako „long Covid”, co można przetłumaczyć na „przedłużony Cowid” albo na stan pokowidowy. Występuje on u osób, które przebyły ostre zakażenie, wytworzyły odpowiednie przeciwciała i zostały uznane za wyleczone.

6 października 2020

Patients With COVID-19 and Other Conditions
https://jamanetwork.com/journals/jama/fullarticle/2770484?guestAccessKey=42ba7c9d-f33b-4af8-984b-0ffcfe2a82ea&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=090320
An abnormally strong proinflammatory response known as “cytokine storm” may play an important role in the pathophysiology of coronavirus disease 2019 (COVID-19), although cytokine storm remains ill defined.

In this study, critically ill patients with COVID-19 with ARDS had circulating cytokine levels that were lower compared with patients with bacterial sepsis and similar to other critically ill patients

High Prevalence of Fatigue Following SARS-CoV-2 Infection Independent of COVID-19 Severity
https://www.medscape.com/viewarticle/938345?src=wnl_edit_tpal&uac=73796MK&impID=2597634&faf=1

Long-term Health Consequences of COVID-19
https://jamanetwork.com/journals/jama/fullarticle/2771581?guestAccessKey=6c60fb00-1424-47b5-abc9-0b502a194f46&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=100520
Current estimates are that approximately 20 million people globally have “recovered”; however, clinicians are observing and reading reports of patients with persistent severe symptoms and even substantial end-organ dysfunction after SARS-CoV-2 infection. Because COVID-19 is a new disease, much about the clinical course remains uncertain—in particular, the possible long-term health consequences, if any.The most commonly reported symptoms after acute COVID-19 are fatigue and dyspnea.

Granted that no long-term data of substantial numbers of patients with various presenting symptoms exist and with comparison groups, and that it is still early in the COVID-19 pandemic, it is possible that large numbers of patients will experience long-term sequelae.

29 września 2020

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19
https://jamanetwork.com/journals/jama/fullarticle/2771160?guestAccessKey=5d14909f-ce8f-4469-ab88-e349e7096c62&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=092420
This study found a higher rate of gastrointestinal complications, including mesenteric ischemia, in critically ill patients with COVID-19 compared with propensity score–matched patients without COVID-19, suggesting a distinct phenotype for COVID-19 compared with conventional ARDS.

1 września 2020

W jakiej kolejności pojawiają się objawy Covid-19?
https://www.esculap.com/news/160014/w-jakiej-kolejnoci-pojawiaj-si-objawy-covid-19?utm_campaign=goniec2033&utm_source=esculap_lekarze&utm_medium=goniec&utm_content=L30&link_id=234873
Z analizy 55 tys. potwierdzonych badaniami przypadków zakażenia koronawirusem SARS-CoV-2 wynika, że zwykle najpierw występują gorączka, kaszel i bóle mięśni, a następnie nudności i wymioty oraz biegunka.

Barometr epidemii (21)
https://www.mp.pl/covid19/covid19-aktualnosci/244496,barometr-epidemii-21
Największy sukces. Pierwsza decyzja nowego ministra zdrowia związana bezpośrednio z pandemią to rozporządzenia zapobiegające przetrzymywaniu w izolacji osób, które albo bezobjawowo przechodzą zakażenie koronawirusem, albo u których objawy ustąpiły, natomiast testy cały czas wykazują obecność materiału genetycznego wirusa w organizmie.

Pinkas: liczymy się ze wzrostem liczby zakażeń
https://www.mp.pl/covid19/covid19-aktualnosci/244488,pinkas-liczymy-sie-ze-wzrostem-liczby-zakazen
Liczymy się z tym, że będziemy mieli wzrost liczby zakażeń koronawirusem, co oczywiście będzie związane z powrotem z wakacji - powiedział główny inspektor sanitarny Jarosław Pinkas. Dodał, że wzrost zakażeń odnotowano też w krajach, gdzie dzieci wróciły do stacjonarnej nauki w szkołach.

Here's how long it took the US to reach 6 million Covid-19 cases
https://edition.cnn.com/world/live-news/coronavirus-pandemic-09-01-20-intl/h_b2168384e6d0848acc82ef10d2bdef80?utm_term=15989592581090514621583d3&utm_source=Coronavirus+Update+-+September+1%2C+2020&utm_medium=email&utm_campaign=240459_1598959258110&bt_ee=sq0uamC2jr8mZ8VZojGfwa4u9D4WY6zsEJEpdPoemN3ilQ2ZMO0pRytelVtCkye7&bt_ts=1598959258110
There have been more than 6 million cases of coronavirus reported in the United States, according to data compiled by Johns Hopkins University.

31 sierpnia 2020

Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30366-0/fulltext?dgcid=hubspot_email_newsletter_tlcoronavirus20&utm_campaign=tlcoronavirus20&utm_medium=email&_hsmi=94148671&_hsenc=p2ANqtz-9tMziq-ri6bmCKTF9hi0rNmJP4dgHrzD6aflcGhh4aB2uLtV6Di-nzlhHRICyVV95AirrjFMd0919qXY_uSlf9TNY_cBHpyx0L3V7o3aHZTQWiqQU&utm_content=94139592&utm_source=hs_email
In this exploratory analysis of 39 patients, ARDS due to COVID-19 was not associated with higher systemic inflammation and was associated with a lower prevalence of the hyperinflammatory phenotype than that observed in historical ARDS data.

26 sierpnia 2020

Direct Evidence for COVID-19 Invasion of Olfactory Complex
https://www.medscape.com/viewarticle/936135?src=wnl_edit_tpal&uac=73796MK&impID=2524268&faf=1
"This is a great piece of evidence that the olfactory tract could potentially serve as a route for invasion of the central nervous system for the novel coronavirus,"

20 sierpnia 2020

Pomoc dla pacjentów po przebyciu COVID-19
https://www.medexpress.pl/pomoc-dla-pacjentow-po-przebyciu-covid-19/78674
24 czerwca europejski oddział WHO opublikował na swojej stronie internetowej broszurę „Support for rehabilitation self-management after COVID-19-related illness” („Wsparcie w samodzielnej rehabilitacji po przebyciu choroby związanej z COVID-19”).

19 sierpnia 2020

W Łodzi trwają pionierskie w skali Europy badania nad wpływem koronawirusa na organizm
https://kardiologia.esculap.com/news/160003/w-odzi-trwaj-pionierskie-w-skali-europy-badania-nad-wpywem-koronawirusa-na-organizm?utm_campaign=goniec2028&utm_source=esculap_wszyscy&utm_medium=goniec&utm_content=L20&link_id=233760
Ministerstwo Zdrowia codziennie załącza w swoim komunikacie dumną liczbę ozdrowieńców. Nie są zdrowi?

2 sierpnia 2020

Global Study to Track COVID-19's Impact on the Brain
https://www.medscape.com/viewarticle/934985?src=wnl_edit_tpal&uac=73796MK&impID=2486825&faf=1
At its annual meeting this week, the Alzheimer's Association announced the launch of a global study to examine the impact of COVID-19 on the brain, as well as policy recommendations to better address the COVID-19 crisis in long-term care facilities.

The study will be led by researchers at the Alzheimer's Association and the University of Texas Health San Antonio, with participation from more than 30 countries and technical guidance from the World Health Organization.

22 lipca 2020

One Third of Outpatients With COVID-19 Are Unwell Weeks Later
https://www.medscape.com/viewarticle/934577?src=wnl_edit_tpal&uac=73796MK&impID=2476328&faf=1
COVID-19 can mean weeks' long illness, even in young adults and those without chronic conditions who have mild disease and are treated in outpatient settings, according to survey results in today's Morbidity and Mortality Weekly Report from the Centers for Disease Control and Prevention (CDC).

20 lipca 2020

Extrapulmonary manifestations of COVID-19
https://edition.cnn.com/2020/06/25/health/coronavirus-younger-people-us-cdc-trnd/index.html?utm_term=15952448552744abb0902836e&utm_source=Coronavirus+Update+-+July+20%2C+2020&utm_medium=email&utm_campaign=227494_1595244855276&bt_ee=5NQtUGA4Um7%2Fsb7gD2SPItkdZNQN81h2X7InkNFcnQxr0yoyzwRALTeOIMxil1%2FF&bt_ts=1595244855276
Although COVID-19 is most well known for causing substantial respiratory pathology, it can also result in several extrapulmonary manifestations. These conditions include thrombotic complications, myocardial dysfunction and arrhythmia, acute coronary syndromes, acute kidney injury, gastrointestinal symptoms, hepatocellular injury, hyperglycemia and ketosis, neurologic illnesses, ocular symptoms, and dermatologic complications

19 lipca 2020

Skin rash should be considered fourth key symptom of COVID
https://www.kcl.ac.uk/news/skin-rash-should-be-considered-fourth-key-symptom-of-covid
A new pre-print study led by King’s College London has found that characteristic skin rashes and ‘COVID fingers and toes’ can occur in the absence of any other symptoms and therefore should be considered as key diagnostic signs of the virus.

15 lipca 2020

COVID-19 Symptoms Can Linger for Months
https://www.medscape.com/viewarticle/933835
Postdischarge assessments of patients who met criteria for SARS-CoV-2 negativity, including a reverse transcriptase-polymerase chain reaction (RT-PCR) test, were conducted from April 21 to May 29. Among the results:

Only 12.6% of the 143 patients were completely free of any COVID-19 symptom
32% of patients had one or two symptoms and 55% had three or more
None had fever or other signs and symptoms of acute illness
53.1% of patients still had fatigue, 43.4% had dyspnea, 27.3% had joint pain, and 21.7% chest pain
44.1% reported worsened quality of life on the EuroQol visual analog scale.

Udar, depresja i psychoza wśród komplikacji po Covid-19
https://neurologia.esculap.com/news/159578/udar-depresja-i-psychoza-wrd-komplikacji-po-covid-19?utm_campaign=goniec2013&utm_source=esculap_lekarze&utm_medium=goniec&utm_content=L27&link_id=232040

12 lipca 2020

Persistent Symptoms in Patients After Acute COVID-19
https://jamanetwork.com/journals/jama/fullarticle/2768351?utm_source=silverchair&utm_campaign=jama_network&utm_content=covid_weekly_highlights&utm_medium=email
In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31 845 confirmed cases as of June 3, 2020).1 Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia/dysgeusia.2-4 However, information is lacking on symptoms that persist after recovery. We assessed persistent symptoms in patients who were discharged from the hospital after recovery from COVID-19.

9 lipca 2020

Włóknienie płuc najczęstsze u leczonych na Covid-19 na intensywnej terapii
https://pulmonologia.esculap.com/news/159480/wknienie-puc-najczstsze-u-leczonych-na-covid-19-na-intensywnej-terapii?utm_campaign=goniec2010&utm_source=esculap_wszyscy&utm_medium=goniec&utm_content=L29&link_id=231707
Ustalenia te przedstawił zespół medyczny z hiszpańskiego Uniwersyteckiego Szpitala Wysp Kanaryjskich. Jak poinformował jeden z jego członków Orlando Acosta, idiopatyczne włóknienie płuc stwierdzano nawet po sześciu do ośmiu tygodniach od przebycia przez zakażonego SARS-CoV-2 choroby.

Pulmonary fibrosis secondary to COVID-19: a call to arms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228737/

8 lipca 2020

Study finds coronavirus associated with neurological complications
https://edition.cnn.com/world/live-news/coronavirus-pandemic-07-07-20-intl/h_6f85a9f582c24dbb57f194acfcbac1ed?utm_term=15942066761919b1fef83c46b&utm_source=Coronavirus+Update+-+July+8%2C+2020&utm_medium=email&utm_campaign=223783_1594206676192&bt_ee=tnzZyzl5mUJd%2B1U3PB3lmcNN0V5IvPUyLA2aSPptZd%2Fjj7Vxxg%2FnAqUgwbRSW262&bt_ts=1594206676192
Coronavirus can lead to neurological complications, including delirium, brain inflammation, stroke and nerve damage, a new University College London (UCL) study published Tuesday in the journal Brain finds.

Neurological and Neuropsychiatric Complications of COVID-19 in 153 Patients: A UK-wide Surveillance Study
Link to artykułu:
https://pubmed.ncbi.nlm.nih.gov/32593341/

14 maja 2020

The Infection That’s Silently Killing Coronavirus Patients
https://www.nytimes.com/2020/04/20/opinion/sunday/coronavirus-testing-pneumonia.html?fbclid=IwAR1uCHNdHZwVrOYyUyBLk7KSMkej3SlWsNAu8l5Gupt5pPIBT818x1xNdn4#click=https://t.co/Z3g1Tjc2zN
Pneumonia is an infection of the lungs in which the air sacs fill with fluid or pus. Normally, patients develop chest discomfort, pain with breathing and other breathing problems. But when Covid pneumonia first strikes, patients don’t feel short of breath, even as their oxygen levels fall. And by the time they do, they have alarmingly low oxygen levels and moderate-to-severe pneumonia (as seen on chest X-rays).
Normal oxygen saturation for most persons at sea level is 94 to 100 percent; Covid pneumonia patients I saw had oxygen saturations as low as 50 percent.
A pulse oximeter can provide early warning of the kinds of breathing problems associated with Covid-19 pneumonia.Credit-19

Hypoxia Management in Ventilated Patients
https://www.lecturio.com/covid-19-case-files/?utm_source=facebook&utm_medium=ad&utm_campaign=HighCPA_Post_COVID-19-Interactive-Case_SA_Interest_Medical-Schools&utm_content=COVID-19-Interactive-Case-1&fbclid=IwAR32mozBBIfhwo8QpYP_cq4Kwv-5RD-DSyhFUyXcULIMATBLIDhgQ9VCZuk

7 maja 2020

Hiperglikemia może istotnie pogarszać przebieg COVID-19.
https://www.medexpress.pl/hiperglikemia-moze-istotnie-pogarszac-przebieg-covid-19/77591
Amid Meagre Testing, Scientists Turn to Sewage as Indicator of Coronavirus Spread in Population
https://www.news18.com/news/india/amid-meagre-testing-scientists-turn-to-sewage-as-indicator-of-coronavirus-spread-in-population-2600991.html
New Delhi: Given that most Indians are unlikely to be tested for COVID-19, scientists are taking a cue from the country's surveillance programme for polio and turning to sewage to get a clearer snapshot of how many people are infected with the coronavirus.

Wastewater epidemiology is a valuable tool to monitor the spread of the novel coronavirus in communities, said Manish Kumar of the Indian Institute of Technology in Gandhinagar who is working with an international team of collaborators on the project.

27 kwietnia 2020

Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility
https://journals.physiology.org/doi/full/10.1152/physrev.00013.2020#.XqVCODEJdxg.facebook

A mysterious blood-clotting complication is killing coronavirus patients
https://www.msn.com/en-us/health/health-news/a-mysterious-blood-clotting-complication-is-killing-coronavirus-patients/ar-BB1336g0?fbclid=IwAR1bkfhcc0du299R30iThUPRA9etWvFNlr-OJrQ5Y-3HJ9LKXuG5l8nDk5E
Komórki w nosie jako brama do zakażenia organizmu przez koronawirusa
https://wiadomosci.onet.pl/swiat/koronawirus-naukowcy-odkryli-znaczenie-komorek-w-nosie-przy-zakazeniu/9gpwk55?utm_source=onetsg_fb&utm_medium=social&utm_campaign=onetsg_fb
Komórki w nosie jako brama do zakażenia organizmu przez koronawirusa
Według naukowców z Uniwersyteckiego Centrum Medycznego w Groningen (UMCG) koronawirus wykorzystuje komórki w nosie, aby dostać się do naszego organizmu. Podobne wnioski potwierdzają także naukowcy z Francji i Wielkiej Brytanii - informuje ''De Telegraaf''.

24 kwietnia 2020

Koronawirusem można się zarazić poprzez kontakt z łzami
Wirus SARS-CoV-2 może replikować się nie tylko w układzie oddechowym, ale także w spojówkach. Lekarze ze szpitala zakaźnego w Rzymie wyodrębnili koronawirusa z łez chorej na COVID-19. Może (ale nie musi) to oznaczać, że koronawirusem można się zarazić poprzez kontakt ze łzami. Więcej: tutaj. Praca oryginalna: tutaj.

Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area – Potrzebujemy takich danych w POLSCE
https://jamanetwork.com/journals/jama/fullarticle/2765184
In this case series that included 5700 patients hospitalized with COVID-19 in the New York City area, the most common comorbidities were hypertension, obesity, and diabetes. Among patients who were discharged or died (n = 2634), 14.2% were treated in the intensive care unit, 12.2% received invasive mechanical ventilation, 3.2% were treated with kidney replacement therapy, and 21% died.,
COVID-19 nie jest tylko chorobą płuc?
https://www.medexpress.pl/covid-19-nie-jest-tylko-choroba-pluc/77412

Gdy pod koniec marca koronawirus rozprzestrzenił się w Nowym Jorku, lekarze z Mount Sinai Hospital zauważyli, że coś dziwnego dzieje się z… krwią pacjentów. Objawy krzepnięcia były wykrywane przez lekarzy różnych specjalizacji w różnych narządach ciała u osób zakażonych. Medexpress 2020-04-22 17:07

24 marca 2020

Lost Sense of Smell May Be Peculiar Clue to Coronavirus Infection
https://www.nytimes.com/2020/03/22/health/coronavirus-symptoms-smell-taste.html?referringSource=articleShare&fbclid=IwAR3ImYJv_S9uV4Lde_DYyQlDzDX5XX1BgGqThc4iht5mEClkRzbvReTTs6c
Doctor groups are recommending testing and isolation for people who lose their ability to smell and taste, even if they have no other symptoms.

Anosmia, the loss of sense of smell, and ageusia, an accompanying diminished sense of taste, have emerged as peculiar telltale signs of Covid-19, the disease caused by the coronavirus, and possible markers of infection.

Biuletyn COVID-19

Nowe kliniczne manifestacje

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