Biuletyn COVID-19: Kobiety w ciąży i noworodki

COVID-19 in Pregnancy: Finally, Some Hard Data
COVID-19 in Pregnancy: Finally, Some Hard Data (medscape.com)
But this paper shows that COVID-19 has some pretty significant effects in pregnancy, and we need to take those risks into account when we consider whether to advise vaccination.

29 grudnia 2020

Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765654?utm_source=silverchair&utm_campaign=altmetric&utm_content=2020_year-end&cmp=1&utm_medium=email
In this cohort study, we found that SARS-CoV-2 can be present in the semen of patients with COVID-19, and SARS-CoV-2 may still be detected in the semen of recovering patients.

12 grudnia 2020

Changes in Preterm Birth Phenotypes and Stillbirthat 2 Philadelphia Hospitals During the SARS-CoV-2Pandemic, March-June 2020
file:///C:/Users/Praca/AppData/Local/Temp/jama_handley_2020_ld_200111_1607178374.44311.pdf
Although these data allow for disaggregation of spontaneous and medically indicated preterm births, no differences in over-all rates of these phenotypes were detected.

25 listopada 2020

COVID-19 and preterm birth
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(20)30457-5/fulltext?dgcid=hubspot_email_newsletter_tlcoronavirus20&utm_campaign=tlcoronavirus20&utm_medium=email&_hsmi=100791296&_hsenc=p2ANqtz-8A8-Gy8NOst_XRFP8O6L0ojslrTevfX4EVdVrfSoDZB2FnDbO2eDw_lDfnvg-17Nbf01iIsgtEU_pBUJGafcnWgi1uoFWEHFeiCDIPi3Na7BWWeB8&utm_content=100791296&utm_source=hs_emailIn their Comment (September, 2020), Vimla Kumari and colleagues
This observation continues to illustrate the indirect effects of COVID-19 on maternal and perinatal health, which we had previously warned about,2 and that there is an urgent need to comprehensively report all important obstetric and neonatal outcomes to highlight both predictable and understandable outcomes (eg, an increase in the incidence of stillbirth3 ) and unexpected patterns of outcomes (eg, the contradictory global evidence about preterm birth rates3 4 5 ).

17 listopada 2020

Konsekwencje zakażenia SARS-CoV-2 u kobiet w ciąży
https://www.medexpress.pl/covid-news-16-11-2020-r/79642
W badaniach opublikowanych przez CDC stwierdzono, że u kobiet w ciąży, chorych na Covi-19 częściej konieczna była wentylacja mechaniczna, ECMO ( pozaustrojowe natlenianie krwi) oraz częściej dochodziło do zgonu.

29 października 2020

Myocardial Effects Seen in Some Pregnant Women With Severe COVID-19
https://bit.ly/2TthEhE
The primary outcomes were elevated cardiac troponins, elevated brain natriuretic peptide (BNP), bradycardia (<60 bpm), and maternal heart rate nadir.
Cardiac troponins and BNP were elevated in 22% (4/18) and 30% (3/10) of women whose biomarkers were measured. Four had transthoracic echocardiograms done, with normal results.

29 września 2020

Association of SARS-CoV-2 Test Status and Pregnancy Outcomes
https://jamanetwork.com/journals/jama/fullarticle/2771110?guestAccessKey=5e50bc5e-48a3-4062-9087-7a5c6fe65ca8&utm_source=silverchair&utm_campaign=jama_network&utm_content=ped_weekly_highlights&cmp=1&utm_medium=email
SARS-CoV-2 test positivity in individuals in labor was associated with a higher prevalence of preeclampsia and lower prevalence of induction of labor. COVID-19 is primarily a respiratory infection but also has systemic effects that may resemble preeclampsia.

In light of other accumulating data, it is already clear that COVID-19 is less severe in pregnancy than the 2 previous coronavirus infections: severe acute respiratory syndrome–related coronavirus (SARS) and Middle East respiratory syndrome–related coronavirus (MERS).

20 sierpnia 2020

Evaluation for SARS-CoV-2 in Breast Milk From 18 Infected Women
https://jamanetwork.com/journals/jama/fullarticle/2769825?guestAccessKey=c0d06f6a-9826-434c-b0c7-f4e582bef498&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=081920
These data suggest that SARS-CoV-2 RNA does not represent replication-competent virus and that breast milk may not be a source of infection for the infant.

17 sierpnia 2020

Researchers Propose Criteria for Confirming Vertical Transmission of SARS-CoV-2
https://www.medscape.com/viewarticle/935509?src=wnl_edit_tpal&uac=73796MK&impID=2505060&faf=1
Dr. Schwartz and colleagues propose that the diagnosis of early-onset neonatal COVID-19 infection be limited to neonates with positive RT-PCR testing for SARS-CoV-2 within the initial 72 hours of life. Those testing positive within the initial 24 hours of life should be considered to have very early-onset COVID-19.

4 sierpnia 2020

Impact of COVID-19 on maternal and child health
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(20)30327-2/fulltext?dgcid=hubspot_email_newsletter_tlcoronavirus20&utm_campaign=tlcoronavirus20&utm_medium=email&_hsmi=92583874&_hsenc=p2ANqtz-_N9BWonS0n9-u386pNTQOSwoVK1vCqp9nL8BhBlhm-ohKKO1vuMDlMKYdJFTRjxPK_lIdCcj4gKlqCEkku1x-T--wVBnHQ66qug7tRu1XRgTC689M&utm_content=92583874&utm_source=hs_email
This analysis highlights the need for continued support from governments to promote and protect breastfeeding, in line with the Global Breastfeeding Collective's call to action during COVID-19.

30 lipca 2020

Possible In Utero SARS-CoV-2 Transmission
https://www.medscape.com/viewarticle/933733?src=mkm_ret_200730_mscpmrk_eumonthly_int&uac=73796MK&impID=2481986&faf=1
"Evidence is stacking up and accumulating that it is indeed possible, though rare," said Claudio Fenizia, PhD, immunology specialist at the University of Milan. Still, none of this should affect the way clinicians practice — at least not yet, he added.

The virus was detected in only two samples of maternal placenta, and both those women had infants with a positive nasopharyngeal swab at birth.

29 lipca 2020

Associations Between Built Environment, Neighborhood Socioeconomic Status, and SARS-CoV-2 Infection Among Pregnant Women in New York City
https://jamanetwork.com/journals/jama/fullarticle/2767631?guestAccessKey=adb93b4d-5250-41ce-bdcf-ad089d7dbab8&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=etoc&utm_term=072820
In this study, SARS-CoV-2 transmission among pregnant women in New York City was associated with neighborhood- and building-level markers of large household membership, household crowding, and low socioeconomic status. These data may aid policy makers in the design of interventions to reduce the spread of SARS-CoV-2.

16 lipca 2020

CDC Revises COVID-19 Risks During Pregnancy as Research Lags
https://www.medscape.com/viewarticle/933914?src=wnl_edit_tpal&uac=73796MK&impID=2461516&faf=1

12 lipca 2020

Study results suggest pregnant women may be able to transmit coronavirus to their babies
https://www.washingtonpost.com/health/another-study-suggests-pregnant-women-can-transmit-coronavirus-to-their-babies/2020/07/09/9f7f333a-c1f2-11ea-b4f6-cb39cd8940fb_story.html?pwapi_token=eyJ0eXAiOiJKV1QiLCJhbGciOiJIUzI1NiJ9.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.gmvzN_SXv9yNVnBr5eQ4gGLPG3dZbrIvnZAknkJGM-Y&utm_campaign=wp_to_your_health&utm_medium=email&utm_source=newsletter&wpisrc=nl_tyh&wpmk=1
Researchers found the coronavirus and antibodies against it in the umbilical cord blood, breast milk, placentas and vaginas of some pregnant infected women, another suggestion that the virus can be passed to fetuses and newborns, according to results of a small study released Thursday.

Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Pandemic
https://jamanetwork.com/journals/jama/fullarticle/2768389?guestAccessKey=3cac324a-3637-476c-8e68-0ea8f3674686&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=071020

6 lipca 2020

COVID-19 u kobiet w ciąży i połogu: informacja dla pracowników opieki zdrowotnej. Tymczasowe wytyczne ISUOG
https://www.mp.pl/ginekologia/wytyczne/inne/237657,covid-19-ukobiet-wciazy-i-pologu-informacja-dla-pracownikow-opieki-zdrowotnej
COVID-19 u kobiet w ciąży i połogu: informacja dla pracowników opieki zdrowotnej. Tymczasowe wytyczne International Society of Ultrasound in Obstetrics and Gynecology (aktualizacja)

11 czerwca 2020

Most pregnant women in UK hospitals with COVID-19 are from minorities, study says
https://www.euronews.com/2020/06/09/most-pregnant-women-in-uk-hospitals-with-covid-19-are-from-minorities-study-says?utm_source=newsletter&utm_medium=special_coverage&utm_campaign=coronavirus&_ope=eyJndWlkIjoiZDViNzM0MWRmOGYyYmNmMzMyMmRiNGUwYmNiY2U5NmEifQ%3D%3D
More than half of pregnant women admitted to hospital in the UK with COVID-19 were from black or other ethnic minorities, a new study in the BMJ medical journal has revealed.

9 czerwca 2020

Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain
https://jamanetwork.com/journals/jama/fullarticle/2767206?guestAccessKey=dd1e70a0-5122-4028-ab3f-dd264a5cbe59&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=060820
Among patients with mild symptoms at presentation, all patients with a vaginal birth had excellent outcomes. In contrast, 13.5% of women undergoing cesarean delivery had severe maternal outcomes and 21.6% had clinical deterioration.

7 czerwca 2020

Caring for Women Who Are Planning a Pregnancy, Pregnant, or Postpartum During the COVID-19 Pandemic
https://jamanetwork.com/journals/jama/fullarticle/2767060?guestAccessKey=5421c3fb-2df4-4b7e-8fe0-1a26f68bd7bc&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=060520
Recommendations for Care of Pregnant Women Confirmed or Suspected to Have Coronavirus Disease 2019 (COVID-19)

27 maja 2020

Prevalence of SARS-CoV-2 Among Patients Admitted for Childbirth in Southern Connecticut
https://jamanetwork.com/journals/jama/fullarticle/2766650?guestAccessKey=8a9972b9-5df0-4202-a659-09b3d2ba1394&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=052620
These findings suggest a low (<3%) prevalence of positive SARS-CoV-2 test results among asymptomatic patients in a pregnant population outside of the highly endemic region of New York City. During this time period, these hospitals, with approximately 2200 licensed beds, experienced a peak (April 21, 2020) of 759 patients admitted for COVID-19, and among US states, Connecticut had the 3rd highest death rate per capita from COVID-19, indicating a substantially affected region.

26 maja 2020

Placental Pathology in COVID-19
https://academic.oup.com/ajcp/advance-article/doi/10.1093/ajcp/aqaa089/5842018?fbclid=IwAR0cl8UH5eMzs-LS3wiuco7anet8YasSoEEJrGQgioj2pYMy96AcuUaO3ls
Only 1 COVID-19 patient was hypertensive despite the association of MVM with hypertensive disorders and preeclampsia. These changes may reflect a systemic inflammatory or hypercoagulable state influencing placental physiology

25 maja 2020

An Analysis of 38 Pregnant Women With COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes
https://pubmed.ncbi.nlm.nih.gov/32180426/
This communication reviews the effects of two previous coronavirus infections - severe acute respiratory syndrome (SARS) caused by SARS-CoV and Middle East respiratory syndrome (MERS) caused by MERS-CoV - on pregnancy outcomes. In addition, it analyzes literature describing 38 pregnant women with COVID-19 and their newborns in China to assess the effects of SARS-CoV-2 on the mothers and infants including clinical, laboratory and virologic data, and the transmissibility of the virus from mother to fetus.

24 maja 2020

Covid-19 appears to attack placenta during pregnancy, study says
https://edition.cnn.com/2020/05/22/health/placenta-covid-19-wellness/index.html?utm_term=15902321066501de685518f03&utm_source=Coronavirus+Update+-+May+23%2C+2020&utm_medium=email&utm_campaign=209330_1590232106653&bt_ee=tcgPMGkFzCKJS7Y7QjF4LHkATz5ZDRKMCAizPVipAkATfrDawCn2hLRWVPcQRRmG&bt_ts=1590232106653

7 maja 2020

Iliana Colonna: enabling positive birth experiences in the time of COVID-19
http://www.euro.who.int/en/health-topics/Health-systems/nursing-and-midwifery/news/news/2020/5/iliana-colonna-enabling-positive-birth-experiences-in-the-time-of-covid-19?utm_source=WHO%2FEurope+mailing+list&utm_campaign=44d6f5a7cf-News_highlights_January_2018_COPY_01&utm_medium=email&utm_term=0_60241f4736-44d6f5a7cf-97074589

27 kwietnia 2020

Universal Screening for SARS-CoV-2 in Women Admitted for Delivery
https://www.nejm.org/doi/full/10.1056/NEJMc2009316
Ile dzieci wymaga opieki na intensywnej terapi?
A new study published in the “Journal of Public Health Management and Practice“ from the University of South Florida (USF) and the Women’s Institute for Independent Social Enquiry (WiiSE), estimates that for each child who requires intensive care for COVID-19, there are 2,381 children infected with the virus. This calculation follows a report from the Chinese Center for Disease Control and Prevention regarding its clinical study of over 2,100 children in China with COVID-19.

22 kwietnia 2020

Severe COVID-19 During Pregnancy and Possible Vertical Transmission – Pojedyńczy przypadek, czy reguła?
https://pubmed.ncbi.nlm.nih.gov/32305046/?fbclid=IwAR0RTBj7YAb1n1bAM-mPvLTm2FL6uUgM1ef10PoJU-0cybHU5n2iisHrE9I

We report a severe presentation of COVID-19 during pregnancy. To our knowledge, this is the earliest reported positive PCR in the neonate, raising the concern for vertical transmission. We suggest pregnant women should be considered as a high-risk group and minimize exposures for these reasons. KEY POINTS: · We report a severe presentation of COVID-19 in pregnancy requiring invasive ventilatory support.. · This is a case of positive RT-PCR in first day of life, suggesting possible vertical transmission.. · There were no detectable maternal antibodies for COVID-19 until after delivery

2 kwietnia 2020

COVID-19 zagrożeniem dla kobiet w ciąży
https://www.medexpress.pl/covid-19-zagrozeniem-dla-kobiet-w-ciazy/77074
Ze względu na stan immunosupresji, jakim jest ciąża, oraz fizjologiczne zmiany adaptacyjne, takie jak podniesienie przepony, zwiększone zużycie tlenu i obrzęk błony śluzowej dróg oddechowych, kobiety w ciąży są szczególnie podatne na zakażenia patogenami układu oddechowego i wykazują małą tolerancje na stany hipoksji.

31 marca 2020

Prof. Lauterbach o opiece nad kobietą w ciąży zakażoną SARS-CoV-2
https://www.termedia.pl/ginekologia/Prof-Lauterbach-o-opiece-nad-kobieta-w-ciazy-zakazona-SARS-CoV-2,37290.html
Chociaż transmisja wirusa od zakażonej matki do rozwijającego się w jej łonie dziecka nie została ostatecznie potwierdzona, to jednak bezpośrednio po urodzeniu istnieje potencjalna możliwość zakażenia dziecka drogą kropelkową.

Covid-19: doctors in final trimester of pregnancy should avoid direct patient contac
https://www.bmj.com/content/368/bmj.m1173?utm_source=etoc&utm_medium=email&utm_campaign=tbmj&utm_content=weekly&utm_term=20200327
Women who are more than 28 weeks pregnant should avoid direct contact with patients—whether or not they could be infected with covid-19, says updated guidance. Those who are less than 28 weeks pregnant, however, can continue to work in patient facing roles provided they use the right personal protection equipment (PPE).

Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China
https://jamanetwork.com/journals/jamapediatrics/fullarticle/2763787?guestAccessKey=dc607cc9-7197-4cc2-8d64-25a5f3f3132b&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamapediatrics&utm_term=mostread&utm_content=olf-widget_03302020
Thirty-three neonates born to mothers with COVID-19, including 3 neonates with COVID-19, were identified. The most common symptom was shortness of breath (4 of 33 neonates). Radiographic findings were nonspecific. No deaths were reported.

30 marca 2020

Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn
https://jamanetwork.com/journals/jama/fullarticle/2763853?guestAccessKey=fba4c309-b020-473d-91d1-52eb5975b4b3&utm_source=silverchair&utm_campaign=jama_network&utm_content=ped_weekly_highlights&cmp=1&utm_medium=email
A neonate born to a mother with COVID-19 had elevated antibody levels and abnormal cytokine test results 2 hours after birth. The elevated IgM antibody level suggests that the neonate was infected in utero.

17 marca 2020

Information on COVID-19 for specific groups: the elderly, patients with chronic diseases, people with immunocompromising condition and pregnant women
https://www.ecdc.europa.eu/en/news-events/information-covid-19-specific-groups-elderly-patients-chronic-diseases-people
There is a limited scientific evidence on the severity of illness among pregnant women and initial data show that they experience similar clinical symptoms as non-pregnant adult patients with COVID-19; at the same time, specific steps to protect them during pregnancy can be taken.

Biuletyn COVID-19

Kobiety w ciąży i noworodki

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